CYP17 genotype predicts serum hormone levels among pre-menopausal women
نویسندگان
چکیده
منابع مشابه
CYP17 genotype predicts serum hormone levels among pre-menopausal women.
BACKGROUND CYP17, which encodes cytochrome P450c17alpha, mediates both steroid 17alpha-hydroxylase and 17,20-lyase activities, and is essential for the production of glucocorticoids and sex steroids. There is evidence that a common polymorphism in CYP17 (T27C) is associated with estrogen levels, making it a potential marker of disease risk. METHODS This is the first study to examine the relat...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2005
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/dei054